Levodopa BP/USP, L-Dopa, CAS 59-92-7

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Model NO.: 99% Min
• Transport Package: 25kg/Drum
• Specification: 99.0%~101.0%
• Trademark: SINOCHEM
• Origin: China
• HS Code: 2922509099
• Production Capacity: 500mt

Product Description

Product Name: Levodopa BP/USP, L-Dopa, CAS 59-92-7
Synonyms: L-3-(3,5-dihydroxyphenyl)aniline; 3,4-dihydroxy-L-phenylalanine; L-levodopa CAS No.: 59-92-7
EINECS No.: 200-445-2
Molecular Formula: C9H11NO4
Molecular Weight: 197.1879
Molecular Structure:
Melting Point: 295°C
Specific Rotation -117° (c=5.3, 1N HCl)
Specifications:

Tests	Specifications
Appearance	White or almost white crystalline powder
Solubility	Slightly soluble in water, Practically insoluble in ethanol, freely soluble in 1M HCl, sparing soluble in 0.1M HCl
Identification	IR spectrum is consistent with EP RS
Appearance of solution	The solution is not more intensely coloured than reference solution BY6
PH	4.5-7.0
Heavy metal	≤10ppm
Loss on drying	≤1.0%
Sulphated ash	≤0.1%
Related substances	A: ≤0.1%
	B: ≤0.5%
	C: ≤0.2%
	Any unknown impurity: ≤0.05%
	Total impurities≤1.0%
Enantiomeric purity  D	≤0.5%
Assay	99.0%~101.0 %
Residual Solvents	I, III Class: Absent
	II Class: ≤3000ppm

Application:
The effect of improving muscle rigidity and slow movement is obvious. Continuous medication is also effective for tremor, salivation, postural instability and dysphagia.
1. Parkinson's disease (primary paralysis agitans)
Symptomatic Parkinson's syndrome (non-drug-induced tremor's palsy syndrome) after encephalitis or with cerebral arteriosclerosis and central nervous system carbon monoxide and manganese poisoning. It can alleviate the symptoms of tremor and paralysis, improve muscle tension, and make limb activities more normal. The effect is better for patients with mild to moderate disease, and worse for severe or elderly patients.
2. Hepatic Encephalopathy
It can make the patient awake and improve symptoms. Hepatic encephalopathy may be related to the abnormality of the central transmitter dopamine. After taking it, it can improve the central function and be effective. It is also believed that levodopa can improve the tolerance of the brain to ammonia, but it cannot improve liver damage and liver function.
3. Neuralgia
Taking it early can relieve neuralgia.
4. Hyperprolactinemia
It can inhibit the thyrotropin releasing hormone in the hypothalamus and excite the prolactin release inhibitor, thereby reducing the secretion of prolactin. It is used to treat hyperprolactinemia and has a certain effect on galactorrhea.
5. Hair loss
The mechanism may be to increase the concentration of catecholamines in the blood to the tissues and promote hair growth.
6. Promote the growth and development of children
It can accelerate the growth and development of children's bones by promoting the secretion of growth hormone. Treat children with hypopituitarism.
Package: 25KG/DRUM
Shelf Life: 36 Months